Applied Therapeutics

Cardioplegia Solution Use in Cardiac Surgery Hypothermic, hyperkalemic cardioplegia solution was first used in open heart surgery in the...

Antiemetic Agents and Postoperative Nausea and Vomiting Impact of Postoperative Nausea and Vomiting PONV is a relatively common (overall ...

Volatile Inhalation Agents Currently, four volatile inhalation agents are available for use in the United States: desflurane, sevoflurane...

Aspiration Pneumonitis Prophylaxis Definition   Aspiration pneumonitis, although uncommon, is a potentially fatal condition that occurs a...

Head Injury and Opioid Analgesia 54. M.C., a 24-year-old male hemophiliac, is admitted to the emergency department (ED) with several minor...

Cimetidine and Methadone 68. One week later, B.D.'s wife calls and says that he is very drowsy and that his speech has started to slur...

Tolerance, Dependence, and Addiction 33. Should tolerance, dependence, and addiction to morphine be an issue in A.J.? Tolerance and physica...

Epidural Analgesia 29. T.M., a 69-year-old man, enters the surgical ICU after surgery for colorectal cancer (lower anterior resection, uret...

Multimodal Pain Management 35. W.W., a 36-year-old male, arrives at the ambulatory surgery center for an inguinal hernia repair. This ...

5-HT3 Antagonists The 5-HT3 antagonists inhibit the action of serotonin in the GI tract and the CNS and thereby block the transmission of e...